Sebastian completed his PhD at the University of Cambridge in 2006 on energy transfer processes in organic semiconductors. After an additional year as a junior research fellow in Prof. Friend's group in Cambridge, he arrived in Sweden in 2007 to investigate conformational dynamics of membrane proteins.
Since 2011 he has turned independent with funding through an Assistant Professorship position, sponsored by the Swedish Research Council, a 'Future Research Leader' research award from the Swedish Foundation of Strategic Research and an ERC starting grant. The goal of his research activities are to explore molecular structural dynamics (see projects).
Elin Claesson, PhD
Elin is currently doing her Ph.D. at the department of Chemistry and Molecular Biology in the Westenhoff group. She has a teaching degree in maths and chemistry but recently, she decided to expand her knowledge in biochemistry. For her master project she worked with structure determination of a sialic acid transporter in the Friemann group. During her Ph.D. she will primarily be working with time-resolved crystallographic studies of phytochromes, a bacterial photoreceptor. Currently she is producing micron-sized crystals for an X-ray free electron laser experiment conducted to probe for dynamical changes in a light-sensitive protein
Keywords: phytochromes, protein expression, crystallization, solution X-ray scattering
Emil Gustavsson, PhD
Emil is currently doing his Ph.D. in the Westenhoff group as a biochemist. He is producing isotope-labelled proteins, focused on bacterial Phytochromes, using both in vitro and in vivo systems. With this he hopes to monitor the proteins active sites and protein dynamics specifically by various NMR and vibrational spectroscopic techniques. He has previously done his M.Sc. in the same group, during which he produced mutant Reaction Centers for studies of the protein-cofactor interactions with ultrafast 2D electronic spectroscopy.
Keywords: Cell-free protein expression, vibrational spectroscopy, infrared, Phytochrome, NMR, isotope
Joachim Kübel, Post Doc.
Joachim studied Chemistry at the Friedrich Schiller University Jena, Germany. For his diploma thesis as well as Ph.D. thesis he has been working with UV/Visible time-resolved spectroscopic methods to characterize the photo-induced dynamics in transition metal complexes as artificial light-harvesting units. Joachim joined the Westenhoff group to study protein dynamics by time-resolved 1D and 2D-IR spectroscopy.
Keywords: 1D and 2D-IR spectroscopy
Léocadie Henry, PhD
Léocadie studied chemical biology at Uppsala University and graduated in June 2015. She did her diploma work at GE Healthcare Lifesciences focusing on protein purification by immobilized-metal affinity chromatography (IMAC). Léocadie started in the Westenhoff group in September 2015. She is currently doing a PhD on the expression and structural analysis by time-resolved Xray crystallography and time-resolved solution Xray scattering of photosensory proteins sensitive to blue light.
Keywords: Protein expression, protein purification, crystallography, SAXS
Linnéa Isaksson, Post Doc.
Linnéa studied biotechnology at Linköping University where she received her masters degree in 2009. Her PhD studies was conducted at the Swedish NMR centre in Gothenburg, studying intrinsically disordered proteins with NMR. Currently she is doing a post-doc in the Westenhoff group. She is mainly interested in cell-free protein expression, a tool for producing recombinant proteins in solution using the biomolecular translation machinery extracted from cells. The synthesized proteins’ function, dynamics and interactions are studied with mainly NMR and Infrared spectroscopy. Her projects are focused on a bacterial Phytochrome, sensitive to light in the red and far-red region of the visible spectrum.
Keywords: Cell-free protein expression, Infrared spectroscopy, NMR, Phytochrome
Matthijs Panman, Post Doc.
Matthijs studied chemistry at the University of Amsterdam (the Netherlands) where he received his masters degree in physical chemistry in 2007. He performed his PhD work at the same university, and focused on investigating the mechanics of synthetic molecular machines with time-resolved infrared spectroscopy. He defended his thesis in 2013, after which he worked on the folding dynamics of small peptides. He joined the Westenhoff group in 2014. Currently, Matthijs is working on visualizing fundamental reaction events in light-triggered chemical reactions with time-resolved WAXS.
Keywords: WAXS, time-resolved IR spectroscopy
Oskar Bertnsson, PhD
Oskar studied bioengineering at Chalmers University of Technology and received his degree in 2013. During the Master program he decided to focus more on biochemistry and did his diploma work in Gergely Katona’s group at the University of Gothenburg. In August 2013 Oskar joined the Westenhoff group as a PhD student. Here, he is studying photosensory protein structural dynamics through X-ray solution scattering techniques (SAXS and WAXS). Primarily his work has aimed at deciphering the signal transduction in blue and red light sensing histidine kinases.
Keywords: protein structural dynamics, X-ray solution scattering, sensor histidine kinase
Petra Edlund, PhD
Petra started her chemistry studies at Lund University, continued with one year as an exchange student in Venezuela and finally earned her Master of Science degree from Gothenburg University. She did her diploma work in Prof. Neutze's group working on purification, crystallization and WAXS studies of Ubiquinol Oxidase from Escherichia coli. Petra started in the Westenhoff group as a project worker and got her PhD position in May 2012. She is currently working on two projects which both includephotactive proteins, The photosynthetic reaction center and phytochromes. Her major project involves crystallisation of phytochromes fortime resolved serial femtosecond crystallography experiments.
Keywords: crystallization, phytochrome, 2D-electronic spectroscopy, protein dynamics